New hope for older myeloma patients: drug combo shows promise without transplant
NCT ID NCT05527340
First seen May 19, 2026 · Last updated May 24, 2026 · Updated 1 time
Summary
This study tests two drug combinations—iberdomide plus dexamethasone, with or without daratumumab—in 140 older adults (65+) newly diagnosed with multiple myeloma who are not eligible for a stem cell transplant. The goal is to see how well these treatments control the cancer and how safe they are, especially in frail patients. Participants take the drugs until the disease worsens or side effects become too severe, meaning this is a long-term management approach, not a cure.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Clínica Universidad de Navarra
Pamplona, Spain
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Hospital General Universitario Gregorio Marañón
Madrid, Spain
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Hospital Son Llatzer
Palma de Mallorca, Spain
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Hospital Universitario 12 de Octubre
Madrid, Spain
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Hospital Universitario Marqués de Valdecilla
Santander, Spain
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Hospital Universitario Virgen del Rocío
Seville, Spain
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Hospital Universitario de Canarias
San Cristóbal de La Laguna, Spain
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Hospital Universitario de Salamanca
Salamanca, Spain
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Hospital Universitario y Politécnico La Fe de Valencia
Valencia, Spain
Conditions
Explore the condition pages connected to this study.