New pill for brain disorders takes first safety step

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Healthy male and female subjects. * Aged between 18 and 55 years. * Written informed consent; willing and able to comply with procedures. * Females will not be pregnant or lactating, and females of childbearing potential and males will agree to use contraception. * Body mass index of 18.0 to 30.0 kg/m2, inclusive; and a total body weight \>50 kg up to a maximum of 110 kg. * The subject must be willing to return to the study centre for study treatment and study-related follow-up procedures as required by the protocol. Exclusion Criteria: * Current or past history of a clinically significant (as judged by the Investigator) cardiovascular, cerebrovascular, respiratory, gastrointestinal, hematologic, renal, hepatic, immunologic, metabolic, urologic, neurologic, dermatologic, psychiatric, or other major disease/condition, as determined by the Principal Investigator or Designee. * Any history of central nervous system problems (e.g. epilepsy, head injury, loss of consciousness). * Any history of malignancy in the previous 5 years involving any organ system (other than localised basal cell carcinoma of the skin). * Body Mass Index: \<18 kg/m2 , or \>30 kg/m2. * Abnormal vital signs, including known history of hypertension, resting oxygen saturation \<95% by pulse oximetry. * ECG at screening or on Day -1 showing QTcF interval \>450 msec in males or \>470 msec in females, or presence of any clinically significant dysrhythmia. * History of hypersensitivity to any medicinal product(s) or severe hypersensitivity/anaphylaxis with unclear aetiology. * Any clinically significant abnormal chemistry values. * Any clinically significant abnormal haematology values. * Blood donation within the past 3 months. * Seropositivity for HBsAg, HCV, HIV 1, or HIV 2. * Has a positive nasopharyngeal test for SARS-CoV-2 within 48h before unit admission. * If female, has a positive highly sensitive urine pregnancy test at Screening or Day 1. * If female and of child-bearing potential, and not meeting the approved criteria for highly effective methods of birth control. * Receipt of any Investigational Drug within the past 6 months. * Use of prescription medication within 14 days prior to dosing and antibiotics within 30 days prior to dosing. * Intake of OTC preparations, vitamins, minerals, herbal remedies within 48h prior to dosing. * Current smokers or history of smoking in previous 6 months. * Current or history of drug, alcohol, nicotine abuse, or excessive coffee (\>5 cups/day) or tea drinking (\>5 cups/day). * Inadequate comprehension of study risks and requirements.