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Gum graft boost: could i-PRF make dental implants look and heal better?

NCT ID NCT07304986

Disease control Sponsor: Al-Azhar University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether adding a substance called i-PRF (made from the patient's own blood) to a standard gum-saving technique (vestibular socket therapy) improves healing and appearance after an immediate dental implant. Twenty-four people with a failing front tooth will receive either the standard procedure or the one with i-PRF. Researchers will check gum color, shape, and bone thickness over 9 months.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
i-PRF (injectable platelet-rich fibrin)
What this could lead to
If successful, this technique could improve gum aesthetics and bone preservation around dental implants placed right after tooth extraction.
What could go wrong
This is a small, early study with only 24 participants, so results may not apply to everyone. The procedure also carries typical risks of dental surgery like infection or implant failure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

24 people

The number who actually took part.

Started

Nov 2023

Expected to finish

Mar 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

15 to 50 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients has one hopeless tooth in the maxillary anterior region with TYPE II according to Elian classification of sockets (10) and sufficient bone apically and palatally. * The presence of a natural contralateral tooth for the tooth being replaced. Exclusion Criteria: * Extraction sockets were grade III. * Acute infection related to hopeless tooth. * Allergy to any material or medication used in the study. * Medically compromised patients according to modified Cornell Medical Index. * Heavy smokers.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Esthetic zone

Contacts and locations

Locations

  • AlAzharU

    Cairo, Nasr City, 11371, Egypt

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