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Could peeling an extra layer during eye surgery prevent repeat detachment?

NCT ID NCT04767555

Disease control Sponsor: Berner Augenklinik Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two types of surgery for people with a detached retina. One group gets standard repair surgery, the other gets an extra step where a thin membrane is peeled away. Researchers want to see if this extra step lowers the chance of re-detachment and improves vision over one year. About 250 adults with a first-time retinal detachment are taking part.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 250 people

The number the study aims to enrol. It can still change while the study runs.

Started

Feb 2022

Expected to finish

Jun 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 110 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * primary rhegmatogenous retinal detachment * of legal age (18 years or older) * in case of bilateral retinal detachment, only the first-affected eye will be included Exclusion Criteria: * pre-existing functional and morphological changes to the macula, hindering visual recovery (amblyopia, trauma, macular degeneration) * advanced retinal detachment with PVR stage C2 or more * eyes pre-operated within six months prior to the development of RD * state after any vitreoretinal surgery * state after complicated cataract surgery, including aphakia and anterior chamber lens implantation * patients with increased risk profiles * myopia magna (≥7 diopters) * advanced diabetic retinopathy * any chronic ocular or systemic inflammatory disease * any other proliferative systemic disease or condition associated with impaired wound healing

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Conditions

The condition(s) this trial relates to.

retinal detachment rhegmatogenous retinal detachment

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Retinal detachment

Contacts and locations

Locations

  • Berner Augenklinik

    Bern, Canton of Bern, 3007, Switzerland

More trials for these conditions

Other studies related to the condition(s) this trial covers.