New MRI technique could revolutionize cystic fibrosis care
NCT ID NCT04259970
First seen Jan 11, 2026 · Last updated Jun 23, 2026 · Updated 26 times
Summary
This study tests whether a special MRI scan can better measure how well a new triple therapy works for cystic fibrosis. 64 participants will have MRI scans before and after starting the therapy. The goal is to find a more sensitive way to track lung health and guide future treatments.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, 45229-3019, United States
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The Hospital for Sick Kids
Toronto, Ontario, M5G 1X8, Canada
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University of Virginia School of Medicine
Charlottesville, Virginia, 22908, United States
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University of Wisconsin
Madison, Wisconsin, 53792, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
CFTR modulator (triple combination therapy) and inhaled contrast for MRI
What this could lead to
If successful, this could provide a more sensitive way to measure lung function in cystic fibrosis, helping doctors tailor treatments and potentially detect early disease changes.
What could go wrong
This is a small, early-phase study focused on imaging methods, not a direct test of a new drug. The results may not apply to all patients or lead to immediate treatment changes.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.