Rural China's hypertension battle: can village doctors turn the tide?
NCT ID NCT03527719
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This large trial tests whether a program led by village doctors can help control high blood pressure in rural China. Over 33,000 participants will receive training, discounted medications, and a simple treatment protocol. The study aims to see if this approach improves blood pressure control and reduces heart disease and dementia over several years.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- village doctor-led multifaceted intervention (training, protocol, incentives, discounted meds)
- What this could lead to
- If successful, this could provide a scalable model for improving blood pressure control in underserved rural areas, potentially reducing heart disease and dementia.
- What could go wrong
- This is a large but early-stage implementation trial; results may not generalize to other regions or healthcare systems. Long-term adherence and sustainability are uncertain.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 33,995 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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May 2018
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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40 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Eligibility criteria for study villages: * The village has a regular village doctor who is willing to participate in the hypertension control project * The village does not plan to merge with other villages within 3 years * The village is at least 2 kilometers away from other participating villages * The village participates in the China New Rural Cooperative Medical Scheme Eligibility criteria of study participants: * Men or women aged ≥40 years * Mean untreated systolic BP ≥140 mm Hg and/or diastolic BP ≥90 mm Hg or mean treated systolic BP ≥130 mm Hg and/or diastolic BP ≥80 mm Hg for individuals without a history of clinical CVD; or mean treated/untreated systolic BP ≥130 mm Hg and/or diastolic BP ≥80 mm Hg for individuals with a history of clinical coronary heart disease, heart failure, stroke, diabetes, or chronic kidney disease * Have lived in a participating village for at least 6 months * No intention to migrate within next 3 years * Taking part in the New Rural Cooperative Medical Scheme * Not pregnant or planning to become pregnant * No malignant tumors and life expectancy ≥3 years * Willing to participate and able to sign informed consent
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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The First Hospital of China Medical University
Shenyang, Liaoning, 110001, China
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