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Large ICU study sheds light on common breathing problem

NCT ID NCT04304339

Knowledge-focused Sponsor: French Society for Intensive Care Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tracked 862 adults in intensive care who had high carbon dioxide levels in their blood (hypercapnia). Researchers aimed to learn how common this condition is, what causes it, and how it affects patient outcomes. No new treatment was tested; instead, the goal was to gather better information to guide future care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

862 people

The number who actually took part.

Started

Dec 2021

Finished

Jul 2022

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The aim of this study is to investigate the epidemiological, clinical determinants and outcomes of patients admitted to ICU with hypercapnic respiratory failure.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * patients ≥18 years old presenting with at least of the following items : 1. respiratory rate ≥ 25/min, 2. paradoxical motion of the abdomen, 3. intercostal retraction AND * a PaCO2 \> 45 cm H20 before ICU admission or within the 12 hours following ICU admission. Exclusion Criteria: * Refusal to give informed consent, * pregnancy, * \< 18 years patient, * dying patient

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Conditions

The condition(s) this trial relates to.

acute respiratory failure Hypercapnia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acute respiratory failure Hypercapnia Intensive care unit syndrome

Contacts and locations

Locations

  • CH Andre Migniot

    Versailles, A, France

  • CHU Nantes

    Nantes, France

  • CHU Toulouse

    Toulouse, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.