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New yellow fever vaccine passes early safety check in small trial

NCT ID NCT05172544

First seen Nov 01, 2025 · Last updated May 19, 2026 · Updated 29 times

Summary

This early-stage trial tested a new inactivated yellow fever vaccine called HydroVax-002 YFV in 26 healthy adults aged 18 to 49. Participants received two shots of either a low or high dose of the vaccine or a placebo, given one month apart. The main goal was to check safety and side effects, while also measuring how well the vaccine triggered an immune response. Results will help decide if larger studies should move forward.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Duke University Health System

    Durham, North Carolina, 27705, United States

Conditions

Explore the condition pages connected to this study.