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New hope for rare leukemia: Triple-Drug combo shows promise in early trial

NCT ID NCT07517510

First seen May 03, 2026 · Last updated May 20, 2026 · Updated 3 times

Summary

This study tests a three-drug combination (homoharringtonine, venetoclax, and azacitidine) in 40 adults newly diagnosed with a rare, aggressive leukemia called mixed-phenotype acute leukemia (MPAL). The goal is to see if this treatment can safely achieve complete remission. Participants must be 18 or older and not have received prior anti-leukemia therapy. The trial is currently enrolling by invitation.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Department of Hematology, Guangdong Second Provincial General Hospital

    Guangzhou, Guangdong, China

Conditions

Explore the condition pages connected to this study.