New drug may help patients breathe easier under anesthesia
NCT ID NCT07252921
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a new medicine called HRS-9190 in 70 adults having planned surgery. The medicine is a muscle relaxant given during anesthesia to help doctors place a breathing tube more easily. Researchers compared it to a standard drug to see if it works as well and is safe. The goal is to provide doctors with another option for managing muscle relaxation during surgery.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 2
Tests whether the treatment actually works, and watches for side effects, in a larger group.
- Participants
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70 people
The number who actually took part.
- Started
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Oct 2025
- Finished
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Dec 2025
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Able and willing to provide a written informed consent 2. Subjects requiring elective general anesthesia surgery 3. Meet specified age and body mass index (BMI) criteria 4. Conform to the ASA Physical Status Classification 5. Use of highly effective contraception for a specified period if applicable Exclusion Criteria: 1. Scheduled for specific high-risk surgical procedures 2. History of significant neuromuscular, cardiovascular, respiratory, or neurological disorders 3. History of conditions affecting drug metabolism or anesthesia risk 4. Abnormal laboratory values indicating significant clinical abnormalities 5. Positive serology for specified infectious diseases 6. Known hypersensitivity to related medications 7. Recent use of medications interfering with neuromuscular function 8. History of mental illness, cognitive impairment, or epilepsy 9. Participation in another clinical trial within a specified period 10. Any other condition deemed unsuitable by the investigator 11. Pregnant or nursing women 12. Unwilling to use birth control during the specified period
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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The First Affiliated Hospital of Wenzhou Medical University
Wenzhou, Zhejiang, 325000, China
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The Third Xiangya Hospital of Central South University
Changsha, Hunan, 410000, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Muscle relaxant dose may hold key to better breathing tube alternative
- Which nerve monitor tells the truth in toddlers?
- Can a common blood pressure drug make anesthesia safer for the very old?
- Muscle mass on CT scans may guide safer anesthesia dosing
- Can a simple skin scrub sharpen surgical monitoring?
- Can a new drug improve muscle relaxation during surgery?