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New targeted drug shows promise for Hard-to-Treat cancers

NCT ID NCT05533463

First seen Nov 01, 2025 · Last updated May 17, 2026 · Updated 32 times

Summary

This early-phase study tests a new drug, HRS-4642, in people with advanced solid tumors that have a specific genetic change called KRAS G12D. The main goal is to find a safe dose and check for side effects. About 102 adults with this mutation who have few other options will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Shanghai Pulmonary Hospital

    Shanghai, Shanghai Municipality, 200433, China

Conditions

Explore the condition pages connected to this study.