DIY swab could revolutionize anal cancer screening for HIV patients

NCT ID NCT07438080

Prevention Sponsor: Centre Hospitalier Universitaire de la Réunion Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether people living with HIV can accurately collect their own swab samples to screen for HPV, a virus that can lead to anal cancer. Researchers will compare self-swabs to those taken by a doctor and ask participants which method they prefer. If self-screening works well, it could make regular cancer screening easier and more private for this high-risk group.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance: HPV self-test (vaginal self-swab)
What this could lead to: If self-screening proves accurate and acceptable, it could make anal cancer screening easier and more accessible for people with HIV, potentially catching pre-cancers earlier.
What could go wrong: This is a small, early-stage study focused on accuracy and acceptability, not on preventing cancer itself. Self-swabbing may be less accurate than a clinician's swab, and results may not apply to other populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 300 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2025

Expected to finish

Mar 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

30 to 65 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Aged 30 to 65, * In a vulnerable situation (beneficiary of a state or departmental social service, or referred by a charity), * Resident in one of the two municipalities targeted by the study, * Supported by the social services of one of the two municipalities targeted by the study, * Having agreed to participate in sexual health awareness meetings organized on site Exclusion Criteria: * Refusing to participate in the study * Having had a hysterectomy

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Conditions

The condition(s) this trial relates to.

human papilloma virus infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HPV

How to take part

Only the study team decides who joins. These are the ways to reach them.

The places running it

2 sites. The list below names each one and where it is.
The official record

ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

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A doctor treating you

A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

DIY swab could revolutionize anal cancer screening for HIV patients

What the study statuses mean