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Can a simple whitening gel erase white spots on teeth?

NCT ID NCT07247760

Symptom relief Sponsor: Universidad Rey Juan Carlos Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only This study
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a 10% carbamide peroxide gel, used at home, can make white spot lesions on teeth less noticeable. About 67 adults with white spots on their front teeth will use the gel and report their satisfaction. The researchers will also check for side effects like tooth sensitivity and gum irritation.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
10% carbamide peroxide gel
What this could lead to
If it works, this could offer a simple, at-home way to reduce the appearance of white spots on teeth without invasive dental work.
What could go wrong
This is a small, early-stage trial with only 67 participants. The treatment may cause tooth sensitivity or gum irritation, and results may not apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 67 people

The number the study aims to enrol. It can still change while the study runs.

Started

Oct 2025

Expected to finish

Jun 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Be over 18 years of age. * Have white spots on teeth between 1.3 and 2.3 or between 3.3 and 4.3. * No previous dental treatment on teeth affected by hypomineralisation lesions. * No active caries lesions at any ICDAS II stage on the anterior teeth. * Patients with satisfactory oral hygiene and periodontal health, who are not undergoing periodontal maintenance and who do not use chlorhexidine mouthwashes. Patients with recessions without sensitivity are included. Exclusion Criteria: * Patients who have previously undergone whitening treatment (less than 5 years ago). * Patients undergoing orthodontic treatment. * Patients with a history of trauma to the front teeth. * Patients with endodontically treated anterior teeth. * Pregnant or breastfeeding patients. * Patients who smoke. * Patients with periodontal disease. * Patients with poor oral hygiene.

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Conditions

The condition(s) this trial relates to.

allergic disease enamel caries Personal Satisfaction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

White spot lesions

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Universidad Rey Juan Carlos

    Alcorcón, Madrid, 28922, Spain

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