Aging breakthrough? supplements aim to boost muscle and brain health in seniors
NCT ID NCT07419633
First seen Feb 23, 2026 · Last updated Jun 22, 2026 · Updated 9 times
Summary
This study tests whether two dietary supplements, HMB and 2-HOBA, can improve muscle mass, physical function, and overall health in adults aged 65 and older. Over 90 days, 120 participants will take one or both supplements or a placebo. Researchers will measure changes in muscle, fitness, and blood markers to see if these supplements support healthier aging.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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RI-MUHC
RECRUITINGMontreal, Quebec, H4A 3J1, Canada
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Beta-Hydroxy-Beta-methylbutyrate (HMB) and 2-hydroxybenzylamine (2-HOBA) dietary supplements
What this could lead to
If successful, these supplements could help older adults maintain muscle strength and physical function, potentially supporting healthier aging.
What could go wrong
This is an early-stage trial with only 120 participants, so results may not apply to everyone. Supplements may not show significant benefits over placebo.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.