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New HIV vaccine combo shows promise in early safety trial

NCT ID NCT05182125

First seen Nov 01, 2025 · Last updated May 19, 2026 · Updated 26 times

Summary

This early-stage study tested two experimental HIV vaccines in 34 healthy, HIV-negative adults to see if they are safe and trigger an immune response. The vaccines use a harmless chimpanzee virus to deliver HIV proteins, followed by a protein boost. The goal is to gather safety data and measure antibody production, not to prevent HIV infection at this stage.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Aurum Institute Klerksdorp CRS

    Klerksdorp, South Africa

  • CAPRISA eThekwini CRS

    Durban, South Africa

  • Emavundleni CRS

    Cape Town, South Africa

  • Isipingo CRS

    Isipingo, South Africa

  • Setshaba Research Centre CRS

    Soshanguve, South Africa

  • Soweto HVTN CRS

    Johannesburg, South Africa

Conditions

Explore the condition pages connected to this study.