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Experimental HIV vaccine shows promise in early safety trial

NCT ID NCT04985760

First seen Nov 06, 2025 · Last updated May 25, 2026 · Updated 37 times

Summary

This study tested an experimental HIV vaccine called Trimer 4571 in 32 adults with HIV who were already on suppressive antiretroviral therapy (ART). The main goals were to see if the vaccine is safe and well tolerated, and whether it can help the immune system produce broadly neutralizing antibodies against HIV. Participants received either a low dose, a high dose, or a placebo, and were monitored for side effects and immune responses.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • AIDS Clinical Trials Unit/The Ohio State University

    Columbus, Ohio, 43210, United States

  • University of Pittsburgh

    Pittsburgh, Pennsylvania, 15213, United States

Conditions

Explore the condition pages connected to this study.