New hope for HIV patients with rare brain infection: stronger drug combo shows promise

This study tested whether adding a powerful HIV drug called enfuvirtide (FUZEON®) to standard antiretroviral therapy could help people with HIV who also have a rare brain infection called progressive multifocal leukoencephalopathy (PML). PML is caused by the JC virus and typically affects people with weakened immune systems. The study involved 30 adults in France who received enfuvirtide for 6 months along with at least two other HIV drugs. Researchers tracked survival and brain function for one year to see if the stronger drug combination could stop PML from getting worse.