Mobile van brings HIV prevention and drug checking to baltimore streets
NCT ID NCT05977881
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed study tested a van-based program in Baltimore that offered drug checking and HIV prevention medication (PrEP) to people who use drugs. Nearly 500 participants were recruited to see if the program helped them start or stay on PrEP and reduce risky behaviors. The goal was to lower both HIV infections and overdose deaths in the community.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- PrEP (pre-exposure prophylaxis) and drug-checking services
- What this could lead to
- If successful, this approach could provide a practical way to lower HIV and overdose rates among people who use drugs in urban areas.
- What could go wrong
- The study is completed but results are not yet widely confirmed; the intervention was offered broadly, so individual impact is hard to measure. Real-world effectiveness may vary.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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493 people
The number who actually took part.
- Started
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Jul 2023
- Finished
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May 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * 18 years or older, * self-reports having used illicit stimulants or opioids at least once in the past 3 months, * self-reports being HIV negative * reports injection drug use in the past 6 months OR reports at least one of the following indicators of sexual HIV risk exposure in the past 6 months: 1. Sexually Transmitted Infection (STI) diagnosis in the past 6 months 2. "Condom-less" vaginal or anal sex in the past 6 months * Willing to provide a urine sample for urine drug screening of substances * Willing to undergo rapid HIV testing * Willing to undergo STI testing Exclusion Criteria: * Determined to be too high or drunk or cognitively impaired, less than 18 years of age * unwilling to provide all required biological specimens (Phase 3 only) * unwilling/unable to give consent
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Johns Hopkins School of Public Health
Baltimore, Maryland, 21205, United States
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