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Can a simple text message help young people with HIV stay on track?

NCT ID NCT05783297

Disease control Sponsor: Amy K. Johnson, PhD, MSW Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether personalized text message reminders can help young people with HIV take their medication consistently. 210 participants from 12 clinics received either standard care or tailored text reminders for 6 months. The goal was to see if the texts improved medication adherence and reduced viral levels.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
personalized SMS text message reminders
What this could lead to
If successful, this could provide a simple, low-cost way to help young people with HIV stick to their medication schedule, improving their health and reducing virus spread.
What could go wrong
This is a completed behavioral study, not a drug trial. The results depend on participants' willingness to respond to texts, and self-reported adherence may not be fully accurate.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

210 people

The number who actually took part.

Started

Apr 2023

Finished

Aug 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

16 to 35 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Diagnosed with HIV-infection and on ART regimen for at least one month 2. Between 16-35 years of age 3. Have a viral load ≥200c/mL and/or report poor adherence (\<90% of pills taken in the last 30 days) 4. Able to receive text messages 5. Can provide informed consent for research component 6. Current patient patient of a participating clinic Exclusion Criteria: 1. Participant is unable to give informed consent 2. Participant is participating in another study related to ART adherence Participants outside of the age range (16-35) will be excluded from the study because this study specifically focuses on youth and young adults living with HIV as they are more likely to disengage from care, delay initiation of ART, and have lower rates of virologic suppression compared to adult populations.

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Conditions

The condition(s) this trial relates to.

HIV infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIV infections

Contacts and locations

Locations

  • AIDS Healthcare Foundation

    Fort Lauderdale, Florida, 33308, United States

  • Baylor College of Medicine

    Houston, Texas, 77030, United States

  • Comprehensive Care Center of Southwest Louisiana

    Lake Charles, Louisiana, 70601, United States

  • Corktown Health Center

    Detroit, Michigan, 48216, United States

  • Duke University

    Durham, North Carolina, 27705, United States

  • Eskenazi Health

    Indianapolis, Indiana, 46202, United States

  • Howard Brown Health

    Chicago, Illinois, 60613, United States

  • Indiana University

    Indianapolis, Indiana, 46202, United States

  • KC Care Health Center

    Kansas City, Missouri, 64111, United States

  • University of Cincinnati

    Cincinnati, Ohio, 45267, United States

  • University of Illinois at Chicago

    Chicago, Illinois, 60612, United States

  • Valley AIDS Council

    McAllen, Texas, 78501, United States

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