Silver-Lined hips: new implant aims to stop repeat infections

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients \> 18 years * Patients indicated for unilateral cementless acetabular and hip stem revision due to chronic periprosthetic infection (according to EBJIS definition): single-stage or two-stage surgical procedure according to clinical standard at the clinical investigation site * According to the assessment of the clinical investigator, the subject is therapy compliant and able to attend the follow-up visits * ASA physical status I - III * Patient's signed written informed consent is available Exclusion Criteria: * Simultaneous participation in another interventional clinical trial (drugs or medical devices studies) * The investigational implant components (femoral and/or acetabular) are not suitable for the patient anatomy or bone defect * Patients who require plate osteosynthesis at the implantation site * Patients with an already implanted silver-coated device * Patients with immunodeficiency, i.e. patients currently receiving immunosuppressive therapy or patients with severe immunodeficiency requiring drug therapy * Patients currently undergoing cancer treatment, e.g. chemotherapy or radiation therapy * Severe soft tissue defects that require local or free flap procedure * Periprosthetic joint infections with evidence of fungal infection * Antibiotic suppression therapy * BMI \> 40 kg/m2 * Pregnancy, breast-feeding, or women of childbearing potential and not taking adequate contraceptive precautions * Known or patient reported hypersensitivity to silver or titanium * Patients held in a custodial setting * Patients in a relationship of dependence on the sponsor, the clinic or the investigator * Patients with contraindication for the investigational and comparator devices: * in case of secondary diseases influencing the function of the joint implant * in case of severe osteoporosis or osteomalacia * in case of poor bone quality and osseous malformations, diseases in the area of the implant fixation, which may primarily or subsequently affect the stability of the joint replacement anchorage * in case of non-regenerative bone conditions with lack of proximal femoral bone support and failure of defect union when use of prosthesis heads with neck length XXL is indicated