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New pain block combo could reduce opioid use in hip fracture seniors

NCT ID NCT07350044

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jul 15, 2026 · Updated 3 times

Summary

This study compares two approaches to pain control in elderly patients having hip fracture surgery: a standard femoral nerve block versus a femoral block plus an additional PENG block. The goal is to see if the combination reduces pain during spinal anesthesia positioning and lowers opioid use in the first 24 hours after surgery. The trial will enroll 68 participants aged 65 and older.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
bupivacaine (a numbing medication) given via nerve blocks
What this could lead to
If successful, this could show that combining two nerve blocks provides better pain relief and less need for opioids in elderly hip fracture patients.
What could go wrong
This is a small, early-stage trial with only 68 participants, so results may not apply to all patients. The added block may not provide significant benefit and carries its own small risks.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

68 people

The number who actually took part.

Started

Jan 2026

Finished

Jun 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

65 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 65 years and older, * Patients scheduled for surgery due to hip fracture, * American Society of Anesthesiologists (ASA) physical status I-III, * Body mass index between 18 and 40 kg/m², * Preoperative fasting duration of approximately 8 hours, * Planned spinal anesthesia, * Ability to provide written informed consent. Exclusion Criteria: * Age below 65 years, * Refusal to participate in the study, * Severe cognitive impairment, dementia, or Alzheimer's disease, * ASA physical status IV or higher, * Body mass index \> 40 kg/m², * Failed spinal anesthesia or conversion to general anesthesia, * Revision hip surgery, * Multiple trauma patients, * Old hip fractures (\>3 weeks), * Active malignancy receiving chemotherapy or radiotherapy, * Active infection requiring antibiotic treatment (except prophylaxis), * Contraindications to regional anesthesia techniques, * Chronic steroid or immunosuppressive therapy, * Use of anti-inflammatory drugs, * Non-fasted patients, * Allergy or intolerance to local anesthetics, paracetamol, tramadol, or other opioids.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Ankara Bilkent City Hospital

    Ankara, Turkey (Türkiye)

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