New pain block combo could reduce opioid use in hip fracture seniors
NCT ID NCT07350044
First seen Jun 26, 2026 · Last updated Jul 15, 2026 · Updated 3 times
Summary
This study compares two approaches to pain control in elderly patients having hip fracture surgery: a standard femoral nerve block versus a femoral block plus an additional PENG block. The goal is to see if the combination reduces pain during spinal anesthesia positioning and lowers opioid use in the first 24 hours after surgery. The trial will enroll 68 participants aged 65 and older.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- bupivacaine (a numbing medication) given via nerve blocks
- What this could lead to
- If successful, this could show that combining two nerve blocks provides better pain relief and less need for opioids in elderly hip fracture patients.
- What could go wrong
- This is a small, early-stage trial with only 68 participants, so results may not apply to all patients. The added block may not provide significant benefit and carries its own small risks.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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68 people
The number who actually took part.
- Started
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Jan 2026
- Finished
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Jun 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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65 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 65 years and older, * Patients scheduled for surgery due to hip fracture, * American Society of Anesthesiologists (ASA) physical status I-III, * Body mass index between 18 and 40 kg/m², * Preoperative fasting duration of approximately 8 hours, * Planned spinal anesthesia, * Ability to provide written informed consent. Exclusion Criteria: * Age below 65 years, * Refusal to participate in the study, * Severe cognitive impairment, dementia, or Alzheimer's disease, * ASA physical status IV or higher, * Body mass index \> 40 kg/m², * Failed spinal anesthesia or conversion to general anesthesia, * Revision hip surgery, * Multiple trauma patients, * Old hip fractures (\>3 weeks), * Active malignancy receiving chemotherapy or radiotherapy, * Active infection requiring antibiotic treatment (except prophylaxis), * Contraindications to regional anesthesia techniques, * Chronic steroid or immunosuppressive therapy, * Use of anti-inflammatory drugs, * Non-fasted patients, * Allergy or intolerance to local anesthetics, paracetamol, tramadol, or other opioids.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Ankara Bilkent City Hospital
Ankara, Turkey (Türkiye)
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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