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Protein power: could extra protein fight muscle loss in diabetes?

NCT ID NCT05457088

Disease control Sponsor: National and Kapodistrian University of Athens Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether eating more protein (1.5 grams per kilogram of body weight daily, instead of the usual 0.8 grams) could help older adults with type 2 diabetes prevent muscle loss and improve muscle function. Twenty-five participants followed either a high-protein or standard-protein diet, and researchers measured changes in muscle mass, strength, and blood sugar levels. The goal was to see if a simple diet change could break the cycle between diabetes and muscle decline.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
high-protein dietary plan (1.5 g/kg/day)
What this could lead to
If it works, this could point toward a simple dietary change to help older adults with type 2 diabetes maintain muscle strength and better control their blood sugar.
What could go wrong
This is a very small completed study (25 people) with no blinding or long-term follow-up. Results may not apply to everyone, and a high-protein diet may not be safe for those with kidney issues.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

25 people

The number who actually took part.

Started

Nov 2021

Finished

Oct 2022

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

50 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * must have been diagnosed with type 2 diabetes mellitus during the last 5 years * must have BMI 18.5-34.9 Exclusion Criteria: * receive dietary supplements * extreme dietary habits * chronic inflammation disease * cancer * autoimmune disease

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Conditions

The condition(s) this trial relates to.

Inflammation Sarcopenia type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

TYPE2 diabetes mellitus

Contacts and locations

Locations

  • National and Kapodistrian University of Athens

    Athens, Attica, Greece

More trials for these conditions

Other studies related to the condition(s) this trial covers.