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Can vitamin e tame COVID-19 inflammation? early trial hints yes

NCT ID NCT07412574

Symptom relief Sponsor: Universidad Veracruzana Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase study tested whether high doses of vitamin E (alpha-tocopherol) could reduce C-reactive protein (CRP), a marker of inflammation, in 56 adults with COVID-19. Participants were randomly assigned to receive vitamin E or a placebo. The results suggest that vitamin E may help lower CRP levels, but because the trial was small and preliminary, more research is needed to confirm these findings.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
high-dose vitamin E (alpha-tocopherol)
What this could lead to
If confirmed, this could point toward a simple, low-cost way to reduce inflammation in COVID-19 patients.
What could go wrong
This is a very early, small trial (56 people) with no long-term follow-up. The results are preliminary and may not hold up in larger studies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Early phase 1

The earliest testing in people: a first look at safety, in a very small group.

Participants

56 people

The number who actually took part.

Started

Sep 2020

Finished

Sep 2021

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Both adult males and females with less than 80 yeas old in age with confirmed covid-19 infection was selected.

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Conditions

The condition(s) this trial relates to.

COVID-19

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COVID -19

Contacts and locations

Locations

  • Faculty of Medicine

    Xalapa, Veracruz, 91120, Mexico

More trials for these conditions

Other studies related to the condition(s) this trial covers.