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Hernia surgery showdown: glue may beat stitches and tacks for pain relief

NCT ID NCT07401082

Symptom relief Sponsor: Cairo University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested three ways to secure mesh during laparoscopic hernia repair: surgical glue, stitches, or metal tacks. 75 adults were randomly assigned to one method. Researchers measured pain, quality of life, and surgery time. The goal is to find which method causes the least discomfort and best recovery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Cyanoacrylate surgical adhesive (Glubran-2®)
What this could lead to
If glue works best, it could mean less pain and faster recovery for hernia patients, with fewer mesh-related discomforts.
What could go wrong
This is a small, completed trial with only 75 people. Results may not apply to everyone, and glue might not hold as well as stitches or tacks over time.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

75 people

The number who actually took part.

Started

Sep 2024

Finished

Oct 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

21 to 60 years

Sex

Male participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 21 to 60 years * Diagnosis of primary (de novo) inguinal hernia * Hernia type: unilateral or bilateral, direct or indirect * Scheduled for elective laparoscopic transabdominal preperitoneal (TAPP) repair * Able to provide informed consent Exclusion Criteria: * Age \<21 or \>60 years * Recurrent inguinal hernia * Complicated hernia (irreducible, incarcerated, obstructed, or strangulated) * Contraindication to laparoscopic surgery or general anesthesia * Significant comorbid conditions making surgery high-risk (ASA class ≥III) * Chronic pain syndrome or regular use of strong analgesics * Allergy to mesh materials (polypropylene) or fixation components (cyanoacrylate, titanium) * Participation in another clinical trial * Inability to complete follow-up or comply with study protocol

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Conditions

The condition(s) this trial relates to.

Hernia, Inguinal Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Inguinal hernia

Contacts and locations

Locations

  • Faculty of Medicine Cairo University

    Cairo, Al-Manial Cairo, 11956, Egypt

More trials for these conditions

Other studies related to the condition(s) this trial covers.