Ancient herbs put to the test: can a plant blend beat metformin for diabetes?
NCT ID NCT07279909
First seen Jan 05, 2026 · Last updated Jun 22, 2026 · Updated 22 times
Summary
This phase 3 trial tests a capsule made from four traditional anti-diabetic herbs (Syzygium cumini, bitter melon, Wrightia tinctoria, and Gymnema sylvestre) in 500 adults with type 2 diabetes. Participants take either the herbal capsule or the standard drug metformin three times daily for six months. The goal is to see if the herbal blend lowers blood sugar and HbA1c as effectively and safely as metformin.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Mehboob Faryal Diagnostic Center
Karachi, Sindh, 74700, Pakistan
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
a blend of four herbs (Syzygium cumini, bitter melon, Wrightia tinctoria, and Gymnema sylvestre) in a capsule
What this could lead to
If it works, this could offer a natural, plant-based option to help control blood sugar in type 2 diabetes, possibly with fewer side effects than standard drugs.
What could go wrong
This is a single study with 500 people, and herbal supplements can vary in potency. It may not prove better than metformin, and long-term safety is still unknown.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.