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New hope for advanced bladder cancer: targeted drug combo enters phase II trial

NCT ID NCT07241793

First seen Nov 21, 2025 · Last updated Apr 30, 2026 · Updated 20 times

Summary

This study tests a new drug (trastuzumab rezetecan) alone or with an immunotherapy (adebrelimab) for people with advanced or metastatic bladder cancer that has a specific protein called HER2. The goal is to see if these treatments can shrink tumors or slow cancer growth. About 96 adults with HER2-positive urothelial carcinoma will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Jiangxi Cancer Center

    RECRUITING

    Nanchang, Jiangxi, 330000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

    NOT_YET_RECRUITING

    Guangzhou, Guangdong, 510000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Sun yat-sen university cancer center

    RECRUITING

    Guangzhou, Guangdong, 510000, China

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Second Affiliated Hospital of Kunming Medical University

    NOT_YET_RECRUITING

    Kunming, Yunnan, 650033, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The fifth Affiliated Hospital of Guangzhou Medcial University

    RECRUITING

    Guangzhou, Guangdong, 510000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Tongji Hospital, Affiliated to Tongji Medical College of Huazhong University of Science and Technology

    NOT_YET_RECRUITING

    Wuhan, Hubei, 430030, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.