Stress and depression may worsen liver disease in korean americans with hepatitis b
NCT ID NCT05117541
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at how factors like chronic stress and depression might speed up liver damage in Korean Americans with chronic hepatitis B. Researchers followed 365 participants over time, collecting health records, hair samples, and interview data. The goal was to understand why some people develop serious liver problems like cirrhosis or cancer, so doctors can find better ways to care for this community.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help doctors better understand and manage liver disease in Korean Americans with hepatitis B, potentially leading to improved treatment strategies.
- What could go wrong
- This is an observational study, not a treatment trial, so it won't directly cure or treat hepatitis B. The findings may not apply to other populations.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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365 people
The number who actually took part.
- Started
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Aug 2021
- Finished
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Mar 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Korean American patients with chronic hepatitis B infection at Liver Disease Prevention Center, Thomas Jefferson University Hospital (TJUH) or Asian Pacific Liver Center (APLC), Coalition of Inclusive Medicine
- Ages
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18 years and older
- Sex
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Anyone
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Provide signed and dated informed consent form * Willing to comply with all study procedures and be available for the duration of the study * Korean-American male or female, age over 18 and older * CHB Patients who have lab and medical record data (including hepatitis B virus \[HBV\] deoxyribonucleic acid \[DNA\] viral load, hepatitis B virus e Antigen \[HBeAg\] status, and liver enzyme values) exist from 2015 or before Exclusion Criteria: * Patients who have received a diagnosis of HCC, although they may have been diagnosed with cirrhosis * Patients who have been diagnosed with other viral infections (hepatitis C virus \[HCV\], human immunodeficiency virus \[HIV\], etc.) * Patients who have total baldness
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Thomas Jefferson University Hospital
Philadelphia, Pennsylvania, 19107, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.