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Scientists test drug cocktails to fight silent liver virus

NCT ID NCT04225715

Summary

This study tested several new combination drug therapies for people with chronic hepatitis B who were already on standard medication. Researchers enrolled 281 participants to compare different drug combinations against a common control group, looking primarily at safety and whether the treatments could reduce signs of the virus in the blood. The trial used a flexible 'platform' design that allowed new treatment arms to be added during the study.

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Contacts and locations

Locations

  • Asan Medical Center / Clinical Trial Center

    Seoul, 138-736, South Korea

  • Auckland Clinical Studies Limited

    Auckland, 1010, New Zealand

  • Beijing Friendship Hospital

    Beijing, 100050, China

  • Changhua Christian Hospital

    Chang-hua, 500, Taiwan

  • China Medical University Hospital

    Taichung, 40447, Taiwan

  • Chuncheon Sacred Heart Hospital

    Gangwon-Do, 200-704, South Korea

  • HIVNAT

    Bangkok, 10330, Thailand

  • Hopital Beaujon

    Clichy, 92118, France

  • Hospital Alvaro Cunqueiro

    Vigo, Pontevedra, 36212, Spain

  • Hospital San Juan de Dios La Serena

    La Serena, 1700000, Chile

  • Huashan Hospital, Fudan University

    Shanghai, 200040, China

  • Kaohsiung Medical University Chung-Ho Memorial Hospital

    Kaohsiung City, 807, Taiwan

  • King College Hospital NHS Foundation Trust

    London, SE5 9RS, United Kingdom

  • Maharaj Nakorn Chiang Mai Hospital

    Chiang Mai, 50200, Thailand

  • Middlemore Clinical Trials

    Auckland, New Zealand

  • Nanfang Hospital, Southern Medical University

    Guangzhou, 510515, China

  • National Cheng Kung Univ Hosp

    Tainan, 00704, Taiwan

  • National Taiwan University Hospital

    Taipei, 10002, Taiwan

  • Queen Mary Hospital

    Hong Kong, Hong Kong

  • Ruijin Hospital Shanghai Jiaotong University School of Medicine

    Shanghai, 200025, China

  • SMG-SNU Boramae Medical Center

    Seoul, 156-707, South Korea

  • Seoul National University College of Medicine, Liver Research Institute

    Seoul, South Korea

  • Siriraj Hospital

    Bangkok, 10700, Thailand

  • Spitalul Clinic Judetean de Urgenta Cluj Napoca

    Cluj-Napoca, 400006, Romania

  • Taichung Veterans General Hospital

    Taichung, 40705, Taiwan

  • The First Hospital of Jilin University

    Changchun, 130021, China

  • Tokuda Hospital Sofia

    Sofia, 1407, Bulgaria

  • Toronto Liver Centre

    Toronto, Ontario, M6H 3M1, Canada

  • Uni of Alberta Hospital

    Edmonton, Alberta, T6G 2S2, Canada

  • University Multiprofile Hospital For Active Treatment "Sveti Ivan Rilski" EAD

    Sofia, 1431, Bulgaria

  • University of Calgary

    Calgary, Alberta, T2N 2T9, Canada

  • Vall d?Hebron Institute of Oncology (VHIO), Barcelona

    Barcelona, 08035, Spain

  • West China Hospital, Sichuan University

    Chengdu, 610041, China

Conditions

Explore the condition pages connected to this study.