Hemophilia Kids' lungs and fitness under the microscope
NCT ID NCT06636565
First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This completed study from Hacettepe University compared lung function, exercise capacity, posture, and physical activity levels between 34 children with hemophilia and healthy controls. Researchers used spirometry, cycling tests, and joint health scores to see if hemophilia affects breathing and fitness. The goal was to understand these differences, not to test a treatment.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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34 people
The number who actually took part.
- Started
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Jul 2024
- Finished
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Jul 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Children with hemophilia and their healthy peers
- Ages
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8 to 18 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Hemophilia group Inclusion criteria: * Having been diagnosed with hemophilia and being clinically stable, * Being between the ages of 8-18, * Being on prophylaxis treatment (a routine treatment), * Being 125 cm or taller, * Being inhibitor negative at the time of enrollment, * To be able to cooperate with the tests to be performed, * Being willing to participate in the study. Exclusion criteria: * Being inhibitor positive at the time of enrollment, * Having a history of acute joint bleeding, * Being unable to bear weight on the extremities, * Having a history of acute intramuscular bleeding, * Having undergone radionuclide synovectomy, * Having a history of surgery on any of the lower extremity joints, * Having a severe cardiovascular, orthopedic or neurological problem that may affect the assessments. Control group Inclusion criteria: * Not having any known internal or chronic disease * Being male between the ages of 8-18 * Having full range of motion in the upper extremity * Having full range of motion in the lower extremity * Not having any history of injury or surgery in the lower extremity * Being 125 cm or taller * Being willing to participate in the study Exclusion criteria: * Having any problem that may affect the tests * Not having full range of motion in the upper extremity * Having a history of injury or surgery in any of the lower extremity joints * Having a neurological deficit * Having pain or movement limitation in the lower extremity
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Hacettepe University Faculty of Physical Therapy and Rehabilitation
Ankara, Ankara, 06100, Turkey (Türkiye)
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Other studies related to the condition(s) this trial covers.
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