Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Hemophilia pain mystery: scientists probe why it lingers

NCT ID NCT07110675

Knowledge-focused Sponsor: Investigación en Hemofilia y Fisioterapia Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at why people with hemophilia and damaged knee or ankle joints feel ongoing pain. Researchers measured pain sensitivity, fear of movement, and anxiety in 146 adults. The goal was to better understand central sensitization—a condition where the nervous system stays in a high-alert pain state—without testing any new treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

146 people

The number who actually took part.

Started

Aug 2025

Finished

Dec 2025

Lead sponsor

A research network

The lead sponsor is a research network or cooperative group.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients with hemophilia and degenerative knee and ankle arthropathy

Ages

18 years and older

Sex

Male participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients diagnosed with haemophilia A and B. * Over 35 years of age. * With a medical diagnosis of bilateral haemophilic ankle arthropathy. * With a clinical assessment using the Hemophilia Joint Health Score greater than 4 points. * On prophylactic treatment with FVIII/FIX coagulation concentrates or monoclonal antibodies. * Sign the informed consent document. Exclusion Criteria: * Patients with neurological or cognitive impairments that prevent them from understanding the questionnaires and physical tests. * Patients who have had ankle or knee haemarthrosis in the 6 months prior to the start of the study. * Patients who have taken analgesic or anti-inflammatory drugs in the 10 days prior to the study. * Patients who are undergoing an intervention (physiotherapy or orthopaedic) at the time of the study.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Hemophilia are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

anxiety disorder Arthralgia Depression hemophilia hemophilia A hemophilia B hemophilic arthropathy Kinesiophobia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hemophilia

Contacts and locations

Locations

  • Universidad de Oviedo

    Oviedo, Principality of Asturias, 33006, Spain

More trials for these conditions

Other studies related to the condition(s) this trial covers.