A 30-second chair test may spot muscle weakness in hemophilia
NCT ID NCT07736976
First seen Jul 30, 2026 · Last updated Jul 31, 2026 · Updated 1 time
Summary
This study compares how well adults with hemophilia (ages 18–35) perform a 30-second sit-to-stand test versus healthy peers of the same age. The goal is to see if this simple test can detect differences in leg strength and endurance linked to joint damage from bleeding. Participants with hemophilia will also have their joint health and daily activity levels assessed to explore connections with test performance.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If differences are found, it could lead to better ways to track physical function in people with hemophilia.
- What could go wrong
- This is a small observational study, so it cannot prove cause and effect or apply to all people with hemophilia.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 58 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Aug 2026
An estimate. Start dates often move.
- Expected to finish
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Sep 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
This study will include adult males aged 18-35 years with a diagnosis of hemophilia A or hemophilia B and age-matched healthy male controls. Participants with hemophilia will be recruited from the members of the Turkish Hemophilia Society. Healthy controls without hemophilia or other bleeding disorders will be recruited from the general population. A total of 58 participants, including 29 individuals with hemophilia and 29 healthy controls, are planned to be included in the study.
- Ages
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18 to 35 years
- Sex
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Male participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Hemophilia Group: * Diagnosis of hemophilia A or hemophilia B * Age between 18 and 35 years * Ability to walk independently * Willingness to participate in the study voluntarily Healthy Control Group: * Age between 18 and 35 years * No history of hemophilia or other bleeding disorders * No history of lower extremity surgery or serious lower extremity injury within the previous 6 months * No neurological, rheumatological, or severe orthopedic disorders * Willingness to participate in the study voluntarily Exclusion Criteria: Hemophilia Group: \- Acute joint bleeding episode within the previous 3 months
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Bahcesehir university
Istanbul, Istanbul, 34353, Turkey (Türkiye)
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