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Pacemaker procedure may cut heart failure deaths in AF patients

NCT ID NCT06833138

First seen Nov 01, 2025 · Last updated May 20, 2026 · Updated 22 times

Summary

This study compares a pacemaker-based procedure (AV node ablation plus physiological pacing) against standard medication in 266 people with permanent atrial fibrillation and heart failure with preserved pumping function. The goal is to see if regularizing the heart rate with pacing reduces deaths and heart failure hospitalizations over two years. Participants will have clinic visits at 3, 12, and 24 months.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CHRU Lille

    NOT_YET_RECRUITING

    Lille, 59000, France

    Contact

  • CHRU de Brest - Hôpital de la Cavale Blanche

    NOT_YET_RECRUITING

    Brest, 29200, France

    Contact

  • CHRU de Caen

    NOT_YET_RECRUITING

    Caen, 14000, France

    Contact

  • CHRU de Tours - Trousseau

    NOT_YET_RECRUITING

    Chambray-lès-Tours, 37170, France

    Contact

  • CHU Grenoble Alpes

    NOT_YET_RECRUITING

    Grenoble, 38043, France

    Contact

  • CHU Poitiers

    RECRUITING

    Poitiers, 86021, France

    Contact

  • CHU de Bordeaux - Hôpital Cardiologique du Haut-Lévèque

    NOT_YET_RECRUITING

    Pessac, 33604, France

    Contact

  • CHU de Nantes - Hôpital Nord Laennec

    NOT_YET_RECRUITING

    Nantes, 44093, France

    Contact

  • CHU de Rouen

    NOT_YET_RECRUITING

    Rouen, 76000, France

    Contact

  • Clinique Millenaire

    NOT_YET_RECRUITING

    Montpellier, 34000, France

    Contact

  • Clinique St Pierre Ottignies

    NOT_YET_RECRUITING

    Ottignies-Louvain-la-Neuve, 1340, Belgium

    Contact

  • GHICL Allome - Hôpital St Philibert

    NOT_YET_RECRUITING

    Lomme, 59462, France

    Contact

  • Groupe Hospitalier La Rochelle-Ré-Aunis

    NOT_YET_RECRUITING

    La Rochelle, 17019, France

    Contact

  • OLV Aalst

    NOT_YET_RECRUITING

    Aalst, 9300, Belgium

    Contact

  • UZ Leuven

    NOT_YET_RECRUITING

    Leuven, 3000, Belgium

    Contact

Conditions

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