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Heart scan may predict who benefits from surgery

NCT ID NCT04508608

Diagnosis Sponsor: Tomsk National Research Medical Center of the Russian Academy of Sciences Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a special heart scan (SPECT) can predict how well patients with ischemic cardiomyopathy will recover after heart surgery. 120 patients underwent imaging at rest and during stress to measure heart function and blood flow. The goal was to find patterns that indicate which patients are likely to see improvement.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this imaging approach could help doctors predict which patients will benefit most from heart surgery.
What could go wrong
This is a small, completed observational study, so results may not apply to all patients. The imaging technique is not yet a standard tool.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

120 people

The number who actually took part.

Started

Sep 2018

Finished

Sep 2021

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients being living in Russian Federation (inc.ethnic minorities)

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: А) For ICM group: 1. History of myocardial infarction (MI) or revascularization (CABG or PCI); 2. \> 75% stenosis of left main or proximal LAD and/ or stenosis of \> 75% of ≥2 epicardial vessels (based on coronary angiography (CA) data); 3. LV EF \<40% and increase in LV volumes according to echocardiography (ECHO) B) For GBPS Control group 1. Absence of obstructive coronary artery lesion; 2. Absence of history of MI and revascularization. C) For CFR Control group 1. Presence of obstructive coronary artery lesion; 2. Indications for coronary artery bypass grafting; Exclusion Criteria (for all groups): 1. Presence of contraindications to the stress test with inotropic stimulation; 2. Inflammatory myocardial diseases; 3. The presence of severe hematological, neurological disorders, other psychosomatic conditions that impede research; 4. Life expectancy of less than 6 months (acute renal and hepatic failure, mental illness, malignant neoplasms of the final stages, unsuitable correction of brain injury).

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Conditions

The condition(s) this trial relates to.

cardiomyopathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Ischemic cardiomyopathy

Contacts and locations

Locations

  • Cardiology Research Institute, Tomsk National Research Medical Centre, Russian Academy of Sciences

    Tomsk, 634000, Russia

More trials for these conditions

Other studies related to the condition(s) this trial covers.