Can a health advocate prevent organ rejection in kids after liver transplant?
NCT ID NCT07279350
First seen Jun 25, 2026 · Last updated Aug 11, 2026 · Updated 3 times
Summary
This study tests whether a health advocate can help families of children who recently had a liver transplant. The advocate works with the family for 90 days to find resources, coordinate appointments, and communicate concerns to the medical team. The goal is to see if this support reduces organ rejection and improves outcomes. About 108 families will take part, with half receiving the advocate and half getting a resource handout.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- health advocate (behavioural intervention)
- What this could lead to
- If it works, this could show that a health advocate helps families manage care after a child's liver transplant, potentially reducing organ rejection and improving long-term health.
- What could go wrong
- This is a small, early-stage trial with only 108 participants, so results may not apply to everyone. The intervention is short (90 days) and may not have lasting effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 108 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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May 2026
- Expected to finish
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Aug 2030
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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0 to 18 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patient \<18 years old at the time of liver transplant * Received a liver transplant within past 90 days * Family endorses material economic hardship on 10-questions Accountable Healthcare Communities screening tool. * Will receive follow-up care for at least 2 years * Family can read or write English or Spanish * A Legally Authorized Representative (LAR) can provide consent, and for children (12-17 years of age, the child is willing/able to provide assent.) * Family has a working phone and smartphone device capable of receiving calls or virtual visits via Zoom. Exclusion Criteria: * Patient has severe cognitive impairment. * 18 years of age or older at the time of consent * Patient unwilling or unable to consent/participate * Patient is a ward of the state (e.g. foster care) since present circumstances may not be reflective of child's past or future circumstances. * Non-English, non-Spanish speakers as ICFs, HIPAA authorization form, surveys, and interviews will only be available in these 2 languages. Languages besides English and Spanish are excluded from this study.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
2 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University of California, San Francisco
RECRUITINGSan Francisco, California, 94158, United States
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University of Pittsburgh Medical Center | Children Hospital of Pittsburgh
RECRUITINGPittsburgh, Pennsylvania, 15224, United States