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Head tilt during thyroid surgery may squeeze the optic nerve

NCT ID NCT07298187

Knowledge-focused Sponsor: Istanbul University - Cerrahpasa Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at how changing the head position during thyroid surgery affects the optic nerve sheath diameter, which can indicate pressure inside the skull. Researchers measured this with ultrasound in 49 patients before and after positioning. They also tracked headache severity after surgery. The goal was to see if certain head positions might raise brain pressure, which could be risky for patients.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help doctors understand how head position affects brain pressure during thyroid surgery, potentially improving patient safety.
What could go wrong
This is a small, completed observational study with only 49 participants. The findings may not apply to all patients or surgeries, and the link to clinical outcomes is uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

49 people

The number who actually took part.

Started

Apr 2025

Finished

Nov 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

ISTANBUL UNIVERSITY-CERRAHPASA

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients aged between 18 and 65, with an ASA score between 1 and 2 according to the American Society of Anesthesiologists (ASA) physical status classification system * whose surgery duration was expected to be less than 4 hours were included in our study. Exclusion Criteria: * liver failure * kidney failure * intracranial masses * history of hydrocephalus, * migraine * chronic hypoxemia or hypercarbic lung disease * additional heart disease * hemodynamic insufficiency * neurological and psychiatric diseases, * glaucoma * patients in whom ocular USG could not provide adequate images * patients with pathological problems involving the eyelid and its surrounding area * patients with diseases such as periorbital cellulitis * patients with preoperative headache complaints * patients with known diseases that could cause increased intracranial pressure * patients who refused to participate in the study were excluded from the study.

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Conditions

The condition(s) this trial relates to.

follicular thyroid adenoma thyroid cancer thyroid gland disorder Thyroid Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Thyroid adenoma Thyroid and parathyroid surgery Thyroid cancer

Contacts and locations

Locations

  • Istanbul University Cerrahpasa

    Istanbul, FATİH, 34000, Turkey (Türkiye)

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