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Electric neck zap may tame Migraine-Like headaches

NCT ID NCT05491915

Symptom relief Sponsor: SPR Therapeutics, Inc. Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a small device that sends mild electrical pulses to nerves in the upper neck to relieve head pain from occipital neuralgia or cervicogenic headache. About 50 adults with these conditions will use the FDA-cleared SPRINT PNS system for up to 60 days. Researchers will measure changes in pain levels and daily interference.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 50 people

The number the study aims to enrol. It can still change while the study runs.

Started

Oct 2022

Expected to finish

Aug 2027

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Key Inclusion Criteria: * Diagnosed cervicogenic headache (CGH) or occipital neuralgia (ON) Key Exclusion Criteria: * Prior cervical or cranial occipital surgery * Implanted electronic device (dependent on implant's intended treatment, location, and electrical current pathway) * Pregnant

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Conditions

The condition(s) this trial relates to.

Headache Neck Pain Post-Traumatic Headache

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cervicogenic headache Occipital neuralgia

Contacts and locations

Locations

  • Center of Clinical Research

    Winston-Salem, North Carolina, 27103, United States

  • Institute of Precision Pain Medicine

    Corpus Christi, Texas, 78414, United States

  • Mayo Clinic Rochester

    Rochester, Minnesota, 55905, United States

  • MedVadis Research

    Waltham, Massachusetts, 02451, United States

  • Pacific Research Institute

    Santa Rosa, California, 95403, United States

  • Pain Specialists of America - Cedar Park

    Cedar Park, Texas, 78613, United States

  • Pain Specialists of America - Round Rock

    Round Rock, Texas, 78681, United States

  • Pain Specialists of America - San Marcos

    San Marcos, Texas, 78666, United States

  • Pain Specialists of America - South Austin - James Casey

    Austin, Texas, 78745, United States

  • University of Utah

    Salt Lake City, Utah, 84108, United States

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