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New drug combo aims to keep aggressive head & neck cancer at bay

NCT ID NCT05433116

Ongoing Disease control Sponsor: Universität des Saarlandes Source: ClinicalTrials.gov ↗

Summary

This study is testing whether adding an oral drug called lenvatinib to an existing immunotherapy (pembrolizumab) works better than the immunotherapy alone to help keep cancer from returning. The treatment is given as 'maintenance therapy' for up to one year after patients complete their initial chemoradiation for locally advanced head and neck cancer. The goal is to see if the combination can help more patients remain cancer-free for two years.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Gemeinschaftspraxis Hämatologie-Onkologie

    Dresden, Saxony, 01307, Germany

  • Hospital Chemnitz, Radiation Oncology

    Chemnitz, Saxony, 09116, Germany

  • Saarland University Medical Center and Saarland University Faculty of Medicine, Clinic for Radiotherapy and Radiooncology

    Homburg, Saarland, 66421, Germany

  • University Hospital Augsburg, Radiation Oncology

    Augsburg, Bavaria, 86156, Germany

  • University Hospital Düsseldorf, Radiation Oncology

    Düsseldorf, North Rhine-Westphalia, 40225, Germany

  • University Hospital Erlangen, Radiation Oncology

    Erlangen, Bavaria, 91054, Germany

  • University Hospital Frankfurt/M, Center for Radiology

    Frankfurt am Main, Hesse, 60590, Germany

  • University Hospital Giessen; Ear, nose and throat clinic

    Giessen, Hesse, 35392, Germany

  • University Hospital Regensburg, Clinic and Polyclinic for Radiotherapy

    Regensburg, Bavaria, 93053, Germany

  • University Hospital Ulm, Otolaryngology & Head and Neck Surgery

    Ulm, Baden-Wurttemberg, 89070, Germany

Conditions

Explore the condition pages connected to this study.

HEAD AND NECK SQUAMOUS CELL CARCINOMA