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Chew your way to a new jawline? science puts hard gum to the test

NCT ID NCT07726511

Knowledge-focused Sponsor: UConn Health Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 24, 2026 · Last updated Jul 24, 2026

Summary

This pilot study investigates whether regularly chewing a hard gum for four weeks can produce measurable changes in facial shape. Twenty healthy adults aged 20 to 40 will chew a standardized hard gum every other day, and researchers will use 3D facial imaging to track any shifts in soft-tissue contours. The goal is to see if a simple chewing exercise can alter facial morphology.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
hard gum chewing (Jawliner®)
What this could lead to
If chewing hard gum measurably alters facial soft tissues, it could point toward a simple, non-invasive way to influence facial appearance or muscle tone.
What could go wrong
This is a very small pilot study with only 20 participants, so results may not apply broadly. Chewing hard gum could also cause jaw soreness or temporomandibular joint discomfort.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 20 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2026

Expected to finish

Jun 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 40 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Healthy, non-smoking adults. * Age 20 to 40 years. * Presence of a full dentition from central incisor to first molar in all four quadrants, excluding second molars. * Stable occlusion with no ongoing orthodontic treatment or myofunctional therapy. * Ability and willingness to comply with the prescribed hard-gum chewing regimen for 4 weeks and attend all study visits. * Ability to provide written informed consent. Exclusion Criteria: * Age younger than 20 years or older than 40 years. * Evident facial asymmetry from a frontal view. * Signs or symptoms of temporomandibular disorders (TMD) according to the Diagnostic Criteria for TMD (DC/TMD). * Less than the normal range of condylar motion during maximum opening and closing. * Parafunctional habits such as bruxism with pain, clenching, or habitual gum chewing for more than 1 hour per day. * History of major craniofacial trauma, orthognathic surgery, or congenital craniofacial anomalies. * Ongoing orthodontic treatment or recent removal of fixed appliances (\<6 months). * Significant malocclusion or missing teeth in the anterior or premolar-first molar region that may affect mastication. * Systemic diseases or medications affecting muscle or bone metabolism. * Previous use of botulinum toxin (Botox) within the last 6 months or anticipated use during the study period. * Pregnancy or lactation. * Allergy or intolerance to the chewing gum ingredients.

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Conditions

The condition(s) this trial relates to.

Facies Fanconi anemia complementation group E

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

FACE

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • UConn Health

    RECRUITING

    Farmington, Connecticut, 06030, United States

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