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Pen and paper: a new hope for Parkinson's hand tremors?

NCT ID NCT07399522

Symptom relief Sponsor: Sara Llamas Velasco Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tested whether doing special handwriting exercises at home for 12 weeks could improve hand function in people with Parkinson's disease. Fifty-three participants were split into two groups: one did the handwriting program, the other did not. The main goal was to see if the exercises improved manual dexterity, measured by a pegboard test.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Calligraphic handwriting exercise program
What this could lead to
If it works, this could offer a simple, home-based way to improve hand function and daily activities for people with Parkinson's disease.
What could go wrong
This is a small, early-stage trial with only 53 participants. The exercises may not lead to meaningful improvements, and results may not apply to all Parkinson's patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

53 people

The number who actually took part.

Started

Jul 2022

Finished

Sep 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

INCLUSION CRITERIA: * Patients aged 40 to 80 years * Clinical diagnosis of Parkinson's disease according to the UK Brain Bank criteria. * Hoehn and Yahr stage 1 to 4 * Assessed in the ON-medication state (approximately 90 minutes after levodopa intake) * Stable antiparkinsonian treatment for at least 4 weeks prior to study entry and maintained throughout the study period EXCLUSION CRITERIA: * Parkinson's disease-related dementia, defined as a Montreal Cognitive Assessment (MoCA) score \< 21 * Upper limb comorbidities unrelated to Parkinson's disease that could interfere ith exercise performance (e.g., arthritis, recent fractures, stroke sequelae, or peripheral neuropathy) * Severe tremor or severe dyskinesias affecting the dominant hand, defined as: * a score ≥ 3 on UPDRS-III items 20 or 22, or * score ≥ 2 on UPDRS-IV item 33

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Conditions

The condition(s) this trial relates to.

Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Parkinson disease (disorder)

Contacts and locations

Locations

  • Hospital Universitario 12 de Octubre

    Madrid, Madrid, Spain

More trials for these conditions

Other studies related to the condition(s) this trial covers.