Gut microbes may hold key to diverticular disease
NCT ID NCT07681505
First seen Jul 02, 2026 · Last updated Sep 03, 2026 · Updated 2 times
Summary
This study investigates whether the bacteria living in the gut influence the development of diverticular disease and acute diverticulitis. Researchers will compare the gut microbiota of people with and without these conditions to identify differences and risk factors. The goal is to better understand the disease and find ways to prevent or treat it.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this research could point toward new prevention or treatment strategies for diverticular disease by targeting the gut microbiome.
- What could go wrong
- This is an observational study, so it cannot prove cause and effect. Results may not lead to direct treatments, and findings may not apply to all populations.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 285 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jun 2027
An estimate. Start dates often move.
- Expected to finish
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Jan 2032
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients attended in outpatient clinics, the gastrointestinal endoscopy unit, and the emergency department at the University Hospital of Navarra
- Ages
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18 years and older
- Sex
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Anyone
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 18 or older. * Signing of the informed consent form. * Assignment to one of the study groups mentioned above. Exclusion Criteria: * An episode of acute diverticulitis located in the right colon or transverse colon. * Antibiotic treatment within the six weeks prior to the episode (except for antibiotics started in the emergency department or within 24 hours prior to sample collection). * Mechanical bowel preparation within the three weeks prior to sample collection. * Diagnosis of colorectal cancer. * Diagnosis of inflammatory bowel disease. * Failure to sign the informed consent form.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Hospital Universitario de Navarra
Pamplona, Navarre, 310013, Spain
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