Could antibiotics make vaccines less effective?
NCT ID NCT06148025
Summary
This study aims to understand if reducing gut bacteria with antibiotics affects how well vaccines protect people. Researchers will give healthy adults either antibiotics or no antibiotics, then give them a BCG vaccine or a placebo. Months later, they will test the immune response by giving a second vaccine challenge (either BCG again or Yellow Fever vaccine) and measuring the body's reaction. The goal is to learn if our gut microbes help train our immune system.
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Contact
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Locations
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South Australian Health and Medical Research Institute
RECRUITINGAdelaide, South Australia, 5000, Australia
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