Stool swap: could gut germs drive eating disorders?
NCT ID NCT07196189
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study takes gut bacteria from women with eating disorders (like anorexia or bulimia) and gives them to mice to see if the mice gain or lose weight differently. The goal is to understand if an unhealthy gut microbiome can influence body weight and eating behavior. It's a basic science study, not a treatment trial.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- fecal microbiota transplant (stool bacteria)
- What this could lead to
- If this works, it could show that gut bacteria play a role in eating disorders, pointing toward new ways to treat them.
- What could go wrong
- This is a very early, small animal study. Results in mice may not apply to humans, and the study only looks at weight, not full eating disorder symptoms.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 84 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Mar 2022
- Expected to finish
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Apr 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients with eating disorders (ED) first-time consultants in order to limit potential interference from previous medical treatments or nutritional support and healthy volunteers not presenting with eating disorders.
- Ages
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18 to 50 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Patients with ED * Women. * Aged 18 to 50. * First consultation in the Nutrition Department of Rouen University Hospital for ED. * Positive SCOFF with diagnosis of anorexia nervosa, bulimia nervosa, or binge eating disorder. * Affiliation with a social security plan. * Patient who has read and understood the information letter and does not object to participating in the study. Healthy Volunteers * Women. * Aged 18 to 50. * Body mass index between 18.5 and 24.9 kg/m². * SCOFF test: no positive response. * No history of ED or active ED (DSM V criteria negative). * Affiliation with a social security plan. * Individual who has read and understood the information letter and does not object to participating in the study. Exclusion Criteria: Patients with ED * Men. * Aged under 18 and over 50. * Negative SCOFF. * Patients who have received antibiotic treatment in the last 3 months. * Patients with a history of IBD or surgical procedures on the digestive tract. * Patient refuses to participate in the study. * Persons deprived of liberty by judicial or administrative order. * Pregnant or breastfeeding women. * Protected persons (guardianship or curatorship). Healthy volunteers * Men. * Aged under 18 and over 50. * SCOFF test with at least one positive response. * History or active ED (DSM V criteria). * Persons who have received antibiotic treatment in the last 3 months. * Person with a history of IBD or surgical procedures on the digestive tract. * Body mass index less than 18.5 or greater than 24.9 kg/m2. * Pregnant or breastfeeding women. * Protected persons (guardianship or curatorship).
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University Rouen Hospital
RECRUITINGRouen, 76031, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- A new approach to curb binge eating may lower diabetes risk in young black women
- Could your phone help rewire binge-eating habits?
- Can a pudding snack reveal how the brain misreads the stomach?
- Could the gut microbiome hold clues to eating disorder recovery?
- Can video therapy match In-Person care for bulimia?