New study tracks arthritis drug persistence in daily life
NCT ID NCT07532226
First seen Jun 27, 2026 · Last updated Aug 28, 2026 · Updated 3 times
Summary
This study follows 200 adults with psoriatic arthritis who are starting guselkumab as part of their normal care. Researchers will track how many patients continue the treatment after one and two years, and why some stop. The goal is to understand how well the drug works in real-world settings, outside of controlled clinical trials.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- guselkumab
- What this could lead to
- If successful, this study could show that guselkumab helps many patients with psoriatic arthritis stay on treatment longer, potentially improving disease control.
- What could go wrong
- This is an observational study, not a controlled trial, so it cannot prove cause and effect. Results may vary by patient and may not apply to everyone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 200 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Apr 2026
- Expected to finish
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Dec 2029
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study population will include participants affected with psoriatic arthritis (PsA) according to classification for psoriatic arthritis (CASPAR) criteria.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion criteria: * Have a confirmed diagnosis of psoriatic arthritis (PsA) as determined by a rheumatologist with reference to ClASsification criteria for Psoriatic ARthritis (CASPAR) * Start guselkumab as a first, second, third, or fourth line of disease-modifying antirheumatic drug (bDMARD) therapy for the indication of PsA as part of standard clinical practice at the time of enrollment into the observational study * Initiating guselkumab treatment according to Summary of Product Characteristics (SmPC) indication * The treatment decision must be taken by the participating rheumatologist prior to, and independently of the patient's inclusion into the study, following clinical practice in accordance with local and overarching guidelines and local regulations * Must have received the information note, given his/her oral agreement and has not objected to the collection of his/her data in accordance with French requirements Exclusion Criteria: * Have already taken a specific interleukin-23 inhibitor (IL-23i) treatment. * Are receiving combination therapy: 2 or more targeted therapies (biotherapy, Janus kinase \[JAK\] inhibitor, phosphodiesterase 4 (PDE4) inhibitor) indicated for PsA/PsO at the same time * Has a contra-indication to guselkumab according to the SmPC (for hypersensitivity or due to active clinically important infection, example active tuberculosis) * Unwilling or unable to participate in long-term data collection * Received an investigational drug (including investigational vaccines) or used an invasive investigational medical device within 30 days before the start of the study ( that is, signing of informed consent) * Currently enrolled in any interventional study or any Janssen-Cilag France-sponsored observational clinical study * Is under guardianship or curatorship, judicial protection, future protection mandate or under family authorization
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Hopital Roger Salengro - CHU Lille
RECRUITINGLille, 59037, France
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Other studies related to the condition(s) this trial covers.
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- Nanobody injection put to the test against psoriatic arthritis
- New study to measure drug levels in breast milk of moms on TREMFYA
- New drug shows promise in taming psoriatic arthritis flares
- New injection targets psoriatic arthritis pain in small trial
- Scientists probe hidden pain pathways in arthritis