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Gum graft showdown: scalpel vs radiofrequency – which works better?

NCT ID NCT07521566

Disease control Sponsor: Dokuz Eylul University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested two methods for preparing gum grafts to treat receding gums. One method uses a scalpel outside the mouth, the other uses a radiofrequency device inside the mouth. Forty-eight patients received one of these grafts along with a surgical gum lift. Researchers checked how much gum tissue grew back and how much leftover tissue remained in the graft, aiming to find a simpler, more comfortable technique.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
de-epithelialized connective tissue graft
What this could lead to
If successful, this could identify a better, more reliable way to prepare gum grafts, leading to more complete gum coverage and less discomfort for patients.
What could go wrong
This is a small, early-stage study with only 48 participants. The results may not apply to all patients, and neither method may prove clearly superior.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 48 people

The number the study aims to enrol. It can still change while the study runs.

Started

Sep 2025

Expected to finish

Jun 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 80 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Voluntary individuals aged between 18 and 80 years * Systemically healthy * Non-smokers * Patients diagnosed with periodontal health following Phase I therapy, with reduced periodontium both clinically and radiographically * Presence of Cairo RT I and RT II gingival recession defects involving maxillary and mandibular anterior and premolar teeth * Presence of at least 1 mm of keratinized gingiva * Individuals not using any medications that may affect periodontal tissue health or wound healing * Absence of any pathology in the palatal mucosa that may interfere with the surgical procedure for connective tissue harvesting Exclusion Criteria: * Teeth with caries, non-carious cervical lesions, or restorations in the gingival recession area * Teeth with endodontic pathology * Pregnant or lactating women * Patients with cardiac pacemakers * Teeth where the cementoenamel junction cannot be clearly identified * Individuals for whom the use of a radiofrequency device may pose a risk * Use of antibiotics or immunosuppressive medications within the last 3 months

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Conditions

The condition(s) this trial relates to.

gingival recession

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Gingival recession, mucogingival surgery Gingival recessions

Contacts and locations

Locations

  • Dokuz Eylul University

    Izmir, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.