Gum arabic supplement shows promise for metabolic syndrome in postmenopausal women
NCT ID NCT04978103
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether taking gum arabic, a natural dietary fiber, can improve markers of metabolic syndrome in 100 postmenopausal women. The researchers looked at changes in inflammation, blood sugar, and cholesterol levels. The goal was to understand how gum arabic might work at a genetic level to reduce inflammation and improve health.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Gum Arabic (Acacia Senegal, a dietary fiber supplement)
- What this could lead to
- If results show gum arabic reduces inflammation or improves metabolic markers, it could point toward a simple dietary supplement to help manage metabolic syndrome in postmenopausal women.
- What could go wrong
- This is a small, completed Phase 2 study with only 100 participants, so findings may not apply broadly. The study measured biological markers, not long-term health outcomes, so real-world benefits are uncertain.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 2
Tests whether the treatment actually works, and watches for side effects, in a larger group.
- Participants
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100 people
The number who actually took part.
- Started
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Dec 2019
- Finished
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Dec 2022
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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45 to 70 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Inclusion criteria Females Menopause Metabolic syndrome based on Adult panel II criteria Signed/verbal consent to participate Exclusion Criteria: * Exclusion criteria 1. Patients with mental or physical disability 2. Use of corticosteroids or any other drug that affects body weight 3. History of Gum Arabic (GA) allergy 4. Chronicrenal or liver disease 5. Chronocinflammatory diseases 6. History of CVA or MI Participants will be asked to maintain their habitually daily diet and level of activity during the period of the study and to continue any previously prescribed medication.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University of Khartoum
Khartoum, 11111, Sudan