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New drug hopes to calm skin lupus flares

NCT ID NCT05629208

First seen Jan 12, 2026 · Last updated May 18, 2026 · Updated 18 times

Summary

This study tested an experimental drug called GS-5718 for people with cutaneous lupus erythematosus (CLE), a condition that causes painful skin rashes and sores. Researchers wanted to see if the drug could reduce skin disease activity and improve symptoms. The study was stopped early, but the goal was to find a safer, more effective treatment for CLE.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • ARENSIA Exploratory Medicine, LLC

    Phoenix, Arizona, 85015, United States

  • Center for Dermatology Clinical Research Inc.

    Fremont, California, 94538, United States

  • Clinical Investigations of Texas

    Plano, Texas, 75075, United States

  • Clinical Research of West Florida, Inc.

    Clearwater, Florida, 33765, United States

  • Dawes Fretzin Clinical Research Group, LLC

    Indianapolis, Indiana, 46250, United States

  • Dept. of Dermatology, Hospital of the University of Pennsylvania, Perelman Center for Advanced Medicine (PCAM)

    Philadelphia, Pennsylvania, 19104, United States

  • Emory University School of Medicine

    Atlanta, Georgia, 30303, United States

  • Gulf Bank Medical Center

    Houston, Texas, 77037, United States

  • HMD Research LLC

    Orlando, Florida, 32819, United States

  • Hospital General de Granollers

    Granollers, 08402, Spain

  • Hospital Universitario de Navarra

    Pamplona, 31008, Spain

  • Reliant Medical Research

    Miami, Florida, 33165, United States

  • Universitatsklinikum Freiburg Klinik fur Dermatologie und Venerologie

    Freiburg im Breisgau, 79104, Germany

  • University of Colorado, Barbara Davis Center, Center for Clinical Research

    Aurora, Colorado, 80045, United States

  • Universitätsklinikum Carl Gustav Carus Klinik und Poliklinik für Dermatologie

    Dresden, 01307, Germany

  • Universitätsklinikum Leipzig AöR Klinik und Poliklinik für Dermatologie, Venerologie und Allergologie Klinische Forschungseinheit (KFE) - Haus 10

    Leipzig, 04103, Germany

  • Yale Center for Clinical Investigation (YCCI)

    New Haven, Connecticut, 06510, United States

Conditions

Explore the condition pages connected to this study.