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Weekly shot could replace daily needles for Growth-Hormone deficient kids

NCT ID NCT07260500

First seen Jan 05, 2026 · Last updated Jun 19, 2026 · Updated 24 times

Summary

This study tests a new weekly growth hormone injection (PEG-rhGH) against a standard daily shot in 72 short children born small for gestational age. The goal is to see if the weekly shot works as well or better for increasing height over 26 weeks. Participants are randomly assigned to one of two doses of the weekly drug or the daily drug.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology

    RECRUITING

    Wuhan, Hubei, 430030, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

PEGylated recombinant human growth hormone (PEG-rhGH) injection

What this could lead to

If successful, this could offer a once-weekly injection option to help short children born small for gestational age grow taller, potentially reducing the burden of daily shots.

What could go wrong

This is an early phase 2 trial with only 72 participants, so results may not apply to all children. The weekly shot may not work as well as the daily one, and side effects like injection site reactions or growth-related issues are possible.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.