New registry aims to unlock secrets of bipolar disorder in kids
NCT ID NCT06665984
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This registry study is enrolling 1,000 children and teens in the Houston area, including those with bipolar disorder, children of parents with bipolar disorder, and healthy controls. Researchers will collect blood and saliva samples, perform brain scans, and conduct interviews to better understand the condition and identify biomarkers. The goal is to improve early detection and guide future research.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this registry could help identify early signs and biological markers of pediatric bipolar disorder, leading to better diagnosis and future treatments.
- What could go wrong
- This is an observational registry, not a treatment trial. It will not directly test any therapy, and results may take years to translate into clinical practice.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 1,000 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Dec 2022
- Expected to finish
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Dec 2046
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Subjects will be recruited from the Harris County Psychiatric Center, Harris Center for Mental Health, Texana Behavioral Healthcare Clinic, and UT Child and Adolescent Outpatient Psychiatry Clinic at Behavioral Science Campus, community referrals, referrals from other health providers, as well as self-referrals.
- Ages
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6 to 17 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria for bipolar patients or offspring of bipolar parents: * Any current mood state (in the case of bipolar subjects) * For bipolar patients: DSM-V criteria for BD type I, BD type II, or BD NOS, as per the administration of the Mini International Neuropsychiatric Interview for Children and Adolescents (MINI-KID) * For the offspring of bipolar parents: at least one parent meeting DSM-V criteria for BD type I or BD type II, or BD NOS as per the administration of the MINI Adult Exclusion Criteria for bipolar patients or offspring of bipolar parents: * Autism Spectrum Disorder (ASD) * Developmental Intellectual Disorder * Severe Neurological Disorder that affects cognitive status (e.g., epilepsy, traumatic brain injury, tubular sclerosis) * Schizophrenia * Uncontrolled or severe medical problem per investigator judgment * For the offspring: parents with a history of any brain diseases, including seizures, stroke, meningitis, encephalitis, dementia, and other degenerative brain diseases; parents with a history of intellectual disability Exclusion Criteria for healthy control subjects: * Any Psychiatric Diagnosis * Any family history of Bipolar Disorder, Psychotic Disorder, Schizophrenia, or Schizoaffective disorder in a first-degree relative * Any family history of a neurological condition in a first-degree relative. * Mental Retardation/Intellectual Disability * Severe Neurological Disorder that affects cognitive status (e.g., epilepsy, traumatic brain injury, tubular sclerosis) * Schizophrenia * Uncontrolled or severe medical problem per investigator judgement Exclusion criteria for annual visits: * Autism Spectrum Disorders (ASD) * Intellectual Developmental Disorder * Severe Neurological Disorder that affects cognitive status (e.g., epilepsy, traumatic brain injury, tubular sclerosis) * Schizophrenia * Uncontrolled or severe medical problem per investigator judgement
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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The University of Texas Health Science Center at Houston
RECRUITINGHouston, Texas, 77479, United States