Grape-Soy combo may reshape your gut bugs
NCT ID NCT04018066
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at whether a supplement made from Concord grape polyphenols and soy protein can change the types of bacteria living in the gut. Researchers gave the supplement to 34 healthy adults aged 18-35 and measured changes in their gut bacteria and blood markers. The goal was to understand how this food combination might influence overall health.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- grape polyphenol-soy protein isolate complex (GP-SPI)
- What this could lead to
- If successful, this could help explain how certain foods change gut bacteria, potentially guiding future dietary recommendations for better health.
- What could go wrong
- This is a small, early-stage study with only 34 healthy participants, so results may not apply to everyone. It only looks at short-term effects on gut bacteria, not long-term health outcomes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
34 people
The number who actually took part.
- Started
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Jun 2019
- Finished
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Dec 2019
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 35 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Healthy as assessed based on a medical evaluation including a comprehensive metabolic panel (CMP) test with values in normal range, medical history and not presently taking any medication 2. Adults between 18 and 35 years 3. BMI 18.5 -29.9 4. Have at least one bowel movement per day 5. Capable of giving written informed consent, which includes compliance with the requirements and restrictions listed in the consent form. Exclusion Criteria: 1. History/current cancer, rheumatoid arthritis immunologic, renal, hepatic, endocrine, neurologic or heart disease, hypertension, diabetes, GI dysfunction, or CMP test results showing values outside of normal range. 2. Cannot provide written informed consent. 3. Exposure to any experimental agent or procedure within 30 days of study. 4. Pregnancy or breast-feeding 5. Taking dietary supplements 6. Current smoker or have smoked within previous 6 months 7. Taking medications regularly (prescription, over the counter, supplements etc.) 8. Treated with antibiotics during the past 6 months 9. Have an allergy to soy or grapes
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Rutgers, The State University of New Jersey
New Brunswick, New Jersey, 08901, United States