New combo therapy targets worst cases of painful gout
NCT ID NCT04762498
Summary
This study tested whether giving KRYSTEXXA (pegloticase) infusions every 4 weeks along with weekly methotrexate pills could better control severe gout in people who don't respond to standard treatments. Researchers followed 50 adults with chronic, uncontrolled gout for up to a year to see if this combination could safely and effectively lower uric acid levels long-term. The goal was to find the right dose for future studies.
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Contacts and locations
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Locations
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Altoona Center for Clinical Research
Duncansville, Pennsylvania, 16635, United States
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Arizona Arthritis & Rheumatology Research, PLLC
Glendale, Arizona, 85306, United States
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Arthritis Clinic: Western Washington Medical Group
Bothell, Washington, 98021, United States
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Arthritis Northwest PLLC
Spokane, Washington, 99204, United States
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Biopharma Informatic, LLC
Houston, Texas, 77043, United States
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East Bay Rheumatology Medical Group, Inc.
San Leandro, California, 94578, United States
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GCP Clinical Research
Tampa, Florida, 33064, United States
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Napa Research Center
Pompano Beach, Florida, 33064, United States
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Orthopedic Physicians Alaska
Anchorage, Alaska, 99508, United States
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ProHealth Research Center
Doral, Florida, 33166, United States
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Shelby Clinical Research, LLC
Shelby, North Carolina, 28150, United States
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The Center for Rheumatology and Bone Research
Wheaton, Maryland, 20902, United States
Conditions
Explore the condition pages connected to this study.